Modelling topical photodynamic therapy treatment including the continuous production of Protoporphyrin IX
نویسندگان
چکیده
منابع مشابه
Modelling topical photodynamic therapy treatment including the continuous production of Protoporphyrin IX.
Most existing theoretical models of photodynamic therapy (PDT) assume a uniform initial distribution of the photosensitive molecule, Protoporphyrin IX (PpIX). This is an adequate assumption when the prodrug is systematically administered; however for topical PDT this is no longer a valid assumption. Topical application and subsequent diffusion of the prodrug results in an inhomogeneous distribu...
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application in photodynamic therapy (PDT). The authors did not mention intralesional PDT, a seldom used technique which potential, though, is in our opinion underrecognized and underestimated. As shown in table 1 , intralesional PDT has been reported to be an effective and safe treatment for skin metastases of breast cancer [2] , superficial and nodular basal-cell carcinoma [3, 4, 6, 7] , squam...
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ژورنال
عنوان ژورنال: Physics in Medicine and Biology
سال: 2016
ISSN: 0031-9155,1361-6560
DOI: 10.1088/0031-9155/61/21/7507